Moisture Surge™ 100-Hour Auto-Replenishing Hydrator

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

A small siloxane used as a spreading and wetting agent. Available cosmetic silicone assessments do not identify a pregnancy-specific concern for normal dermal exposure. Volatile or spray products should be used with ordinary ventilation.

Sources: CIR: safety assessments of dimethicone, methicone and substituted methicone polymers; European Commission CosIng ingredient inventory for Trisiloxane.

Sugar-derived humectant used to help bind water and improve skin feel. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.

Sources: CIR: Safety Assessment of Monosaccharides, Disaccharides, and Related Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

This sugar or sugar alcohol is used as a humectant and skin-conditioning ingredient. Cosmetic Ingredient Review assessments support these saccharides in current cosmetic use, with no pregnancy- or breastfeeding-specific concern identified for normal topical exposure.

Sources: CIR: Safety Assessment of Monosaccharides Disaccharides and Related Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-monosaccharides-disaccharides-and-related-ingredients-used-cosmeti

Polymer thickener used to stabilise emulsions. Large-molecule ingredient with low systemic absorption.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

A humectant that helps skin and hair retain water. Cosmetic safety reviewers concluded that hydroxyethyl urea is safe in current cosmetic use when formulated to be non-irritating; reproductive and developmental data reviewed for the assessment did not identify a pregnancy-specific concern from normal topical exposure.

Sources: CIR: Safety Assessment of Hydroxyethyl Urea https://www.cir-safety.org/supplementaldoc/safety-assessment-hydroxyethyl-urea-used-cosmetics-0

Camellia sinensis (green tea) leaf extract is used as an antioxidant botanical; topical cosmetic use is considered low concern with no known pregnancy or breastfeeding risks, though rare sensitivities are possible.

Sources: CIR; EU/UK Cosmetics Regulation

Milk-thistle extract is a botanical cosmetic ingredient. This generic extract name must not be silently equated with fruit extract, seed extract, seed oil or a standardized oral silymarin supplement. Direct pregnancy studies of the exact topical extract were not identified. Oral-herbal pregnancy cautions reflect a different exposure and cannot be directly transferred to normal topical cosmetic use; no pregnancy-specific topical hazard was identified. Asteraceae allergy remains possible.

Sources: LactMed milk thistle identity, lactation evidence and allergy cautions https://www.ncbi.nlm.nih.gov/sites/books/NBK501771/; EMA assessment of oral Silybum marianum fruit preparations, not equivalent to cosmetic extract https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-silybum-marianum-l-gaertn-fructus_en.pdf; study of topical silymarin constituents and skin tolerance https://pmc.ncbi.nlm.nih.gov/articles/PMC4002699/

A botanical extract, plant water or plant juice used for conditioning, soothing or antioxidant support. Direct pregnancy studies of this exact cosmetic material were not identified, but no reproductive or developmental hazard was identified for normal topical exposure. Oral herbal or medicinal use is outside this classification.

Sources: European Commission CosIng ingredient inventory; CIR botanical safety framework and relevant plant-derived ingredient assessments; no ingredient-specific human pregnancy study of normal topical cosmetic use was identified.

saccharomyces lysate extract is a fermentation-, microbial- or algae-derived cosmetic conditioning material. The assessment applies to the defined cosmetic ingredient rather than live organisms or oral supplements. No pregnancy-specific concern was identified for normal topical use; formulation purity and sensitivity remain relevant.

Sources: CIR assessments of microbial polysaccharides, fermentation-derived and algae-derived cosmetic ingredients; CIR Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

A botanical extract or plant water used for conditioning, soothing or antioxidant support. Direct pregnancy studies of this exact cosmetic material were not identified, but no reproductive or developmental hazard was identified for normal topical exposure. Oral herbal or medicinal use is outside this classification.

Sources: European Commission CosIng; CIR botanical safety framework and relevant plant-family assessments; no ingredient-specific human pregnancy study of normal topical cosmetic use was identified.

Botanical skin-conditioning ingredient used in soothing and hydrating formulas. Reviewed cosmetic safety sources support current cosmetic use provided anthraquinone levels do not exceed the limits addressed in the safety assessment; no pregnancy- or breastfeeding-specific topical concern was identified in the material reviewed.

Sources: CIR: Safety Assessment of Aloe-derived Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

thermus thermophillus ferment is a fermentation-, microbial- or algae-derived cosmetic conditioning material. The assessment applies to the defined cosmetic ingredient rather than live organisms or oral supplements. No pregnancy-specific concern was identified for normal topical use; formulation purity and sensitivity remain relevant.

Sources: CIR assessments of microbial polysaccharides, fermentation-derived and algae-derived cosmetic ingredients; CIR Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

Methylxanthine used in cosmetics (e.g., de-puffing/firming and antioxidant support). No pregnancy-specific contraindications are identified for topical cosmetic use.

Sources: CIR (Methylxanthines); PubMed (NLM)

Sugar alcohol humectant used to help maintain water content at the skin surface. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Mannitol, Sorbitol, and Xylitol as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Synthetic palmitoylated peptide used in topical cosmetic anti-aging and skin-conditioning formulas. Reviewed topical peptide literature lists palmitoyl hexapeptide-12 among topically used matricin-style peptides and does not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.

Sources: Schagen SK. Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics. 2017;4(2):16. doi:10.3390/cosmetics4020016; CIR Expert Panel safety assessment of tripeptide-1, hexapeptide-12 and related derivatives.

Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Humectant and preservative booster used to support product stability. Low systemic exposure expected from topical cosmetic use.

Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)

An ethoxylated oleyl-alcohol surfactant and emulsifier. CIR included Oleth-10 in the safe conclusion for alkyl PEG ethers when formulated to be non-irritating. Appropriate ethoxylation impurity controls apply; no pregnancy-specific concern was identified for normal topical cosmetic exposure.

Sources: CIR: Safety Assessment of Alkyl PEG Ethers as Used in Cosmetics https://cir-safety.org/sites/default/files/QRT-Update-100824_0.pdf

sodium polyaspartate is a high-molecular-weight cosmetic polymer or film former. Dermal absorption is expected to be limited when manufactured with appropriate residual-monomer and impurity controls. Relevant CIR polymer assessments did not identify a pregnancy-specific concern for normal topical use; airborne powder or spray droplets should not be inhaled.

Sources: CIR Amended Safety Assessment of Acrylates Copolymers https://cir-safety.org/ingredient/acrylates-copolymer; CIR vinylpyrrolidone-polymer assessment.

Aloe vera and Aloe barbadensis are synonyms. Controlled cosmetic material with anthraquinones at or below 50 ppm differs from crude latex/oral preparations with experimental reproductive concerns. Ordinary intact-skin use identifies no pregnancy-specific concern as an exposure inference; human pregnancy and milk-transfer evidence remain limited. Oral laxatives and enhanced delivery are excluded.

Sources: https://journals.sagepub.com/doi/pdf/10.1080/10915810701351186

A lysate produced from Lactobacillus fermentation and used for skin conditioning. Cosmetic safety reviewers concluded that Lactobacillus ferment lysate is safe in current practices of use and concentration.

Sources: CIR: Lactobacillus Ferment Lysate final safety assessment, September 2025; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

Humectant saccharide complex used to improve surface hydration and reduce transepidermal water loss. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Saccharide Humectants / Saccharide Isomerate, etc.; EU CosIng / cosmetics regulatory inventory

Hydrogenated emulsifier used to support skin barrier feel. Not associated with pregnancy-specific concerns.

Sources: Cosmetic Ingredient Review (US)

Tocopheryl acetate (vitamin E derivative) is used as an antioxidant and skin-conditioning ingredient; it is considered low concern in topical use with no known pregnancy or breastfeeding risks at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Polymer thickener and stabiliser used in creams and sunscreens. Low systemic exposure expected.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

A high-molecular-weight moisturising and texture polymer. Cosmetic safety reviewers concluded that glyceryl polymethacrylate is safe in current cosmetic practices. Dermal absorption of the intact polymer is expected to be limited, and residual monomers should be controlled.

Sources: CIR: Final safety assessment of Glyceryl Polymethacrylate, June 2022; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

pH adjuster and buffer used to stabilise formulations. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Tromethamine as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

A small polyethylene glycol used as a humectant and solvent. Cosmetic safety reviewers concluded that PEG-8 is safe at current cosmetic concentrations, but PEG ingredients should not be used on damaged skin and manufacturing impurities must be controlled. No pregnancy-specific concern was identified for compliant topical use.

Sources: CIR: Final Report on the Safety Assessment of Polyethylene Glycols https://cir-reports.cir-safety.org/view-attachment/?id=0ca16b53-8e74-ec11-8943-0022482f06a6

Solvent and humectant used to improve texture and ingredient solubility in topical cosmetics. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR cosmetic ingredient safety references for alkane diols/glycols; EU CosIng / cosmetics regulatory inventory

A stable vitamin C derivative used for antioxidant and skin-conditioning effects. Cosmetic safety reviewers concluded that magnesium ascorbyl phosphate is safe in current practices of use and concentration.

Sources: CIR: Ascorbyl ingredients conclusion, IJT 24(Suppl. 2), 2005; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

pH adjuster used in small amounts to maintain product stability. Not associated with pregnancy-specific concerns.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

Disodium EDTA is a chelating agent used to improve formula stability and performance; it is considered low concern in topical cosmetic use, with no known pregnancy or breastfeeding risks at typical concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Buffering and chelating ingredient used to control pH and formulation stability. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Citric Acid, Inorganic Citrate Salts, and Alkyl Citrate Esters as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Preservative widely used in foods and cosmetics. Considered safe at regulated concentrations with low systemic exposure from topical use.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

Preservative widely used in foods and cosmetics. Considered safe at regulated concentrations with low systemic exposure from topical use.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

A Colour Index or lake name for a regulated cosmetic colour additive. Permitted product areas differ by colour, and certified colours must meet applicable identity and purity specifications. No pregnancy-specific concern was identified for compliant topical cosmetic use.

Sources: FDA: Regulatory Status of Color Additives https://hfpappexternal.fda.gov/scripts/fdcc/index.cfm?set=ColorAdditives; FDA: Color Additives Permitted for Use in Cosmetics https://www.fda.gov/cosmetics/cosmetic-ingredient-names/color-additives-permitted-use-cosmetics; 21 CFR Parts 73, 74 and 82.

Also known as FD&C Yellow No. 5 or tartrazine, this certified colour additive is used in cosmetics and other regulated products. FDA permits its use in cosmetics, including the eye area, when identity, purity, certification and use requirements are met. Rare allergy-like reactions can occur, but no pregnancy-specific concern is identified for normal use in a compliant finished cosmetic.

Sources: FDA: Regulatory Status of FD&C Yellow No. 5 / C.I. 19140 https://www.hfpappexternal.fda.gov/scripts/fdcc/index.cfm?id=FDCYellow5&set=ColorAdditives; FDA: Color Additives and Cosmetics Fact Sheet https://www.fda.gov/industry/color-additives/color-additives-and-cosmetics-fact-sheet