Naturium
Naturium Vitamin C Complex Serum
Low risk76/100
Is it suitable during pregnancy?
MamaSkin rates the recorded formula for Naturium Azelaic Topical Acid 10% as Low risk (76/100). Review the ingredient context and any manual-review explanation before deciding.
Why this rating?
The recorded formula includes 1 ingredient entry with a risk flag: Phenoxyethanol (Low risk). These are ingredient-level flags; they do not replace the stored product assessment or account for every formulation detail.
18 of 18 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.
How we assess productsIngredient breakdown
The recorded formula, with evidence behind each rating. Unmatched ingredients are marked Not assessed in grey.
Ingredient ratings and evidence
Higher-risk flags first. Open an ingredient for evidence.
Phenoxyethanol
Low risk
Phenoxyethanol is a preservative permitted in EU cosmetics up to 1.0%. The SCCS concluded it is safe for cosmetic use at that level, including when considering higher cosmetic exposure scenarios in infants and young children. Main practical concern is irritation/stinging on very sensitive or compromised skin rather than a pregnancy- or breastfeeding-specific risk.
Sources: SCCS/1575/16: Phenoxyethanol opinion https://health.ec.europa.eu/publications/phenoxyethanol_en
Water
No known risks
Water (Aqua) is the standard purified water used as a cosmetic solvent. It has no pregnancy-specific risk in normal topical use.
Sources: https://pubchem.ncbi.nlm.nih.gov/compound/Water, https://single-market-economy.ec.europa.eu/sectors/cosmetics/cosmetic-ingredient-database/cosing-glossary-ingredients_en
Propanediol
No known risks
Solvent and humectant used to improve texture and ingredient solubility. Low systemic exposure expected from topical cosmetic use.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Potassium Azeloyl Diglycinate
No known risks
Potassium Azeloyl Diglycinate is a water-soluble azelaic-acid and glycine derivative used for skin conditioning and tone support. The intact cosmetic ingredient is not the same as free azelaic acid, and no reproductive or developmental hazard signal was identified for normal topical cosmetic exposure.
Sources: European Commission CosIng ingredient inventory; published cosmetic literature on potassium azeloyl diglycinate and azelaic-acid derivatives. No ingredient-specific pregnancy studies were identified.
Polyacrylate Crosspolymer-6
No known risks
Large polymer thickener and stabilizer used in gels, serums and creams. Systemic exposure from topical cosmetic use is expected to be low, with no pregnancy- or breastfeeding-specific concern identified in reviewed cosmetic references.
Sources: CIR cosmetic ingredient safety references for acrylates/polyacrylate crosspolymers; EU CosIng / cosmetics regulatory inventory
Show all 18 ingredients
Niacinamide
No known risks
Niacinamide (vitamin B3) is widely used for barrier support and tone/texture benefits, and is generally considered safe in pregnancy and breastfeeding when used topically at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
3-O-Ethyl Ascorbic Acid
No known risks
A stable ether derivative of vitamin C used as an antioxidant and brightening ingredient. Pregnancy-specific topical studies are limited, but no pregnancy-specific contraindication was identified in the reviewed literature. Published case reports describe allergic contact dermatitis, so local sensitivity remains possible and this classification should not be read as proof that irritation cannot occur.
Sources: CIR: Safety Assessment of Ethers of Ascorbic Acid https://www.cir-safety.org/sites/default/files/ethers_of_ascorbate.pdf; PubMed: 3-O-ethyl-L-ascorbic acid topical delivery https://pubmed.ncbi.nlm.nih.gov/31517290/; PubMed: allergic contact dermatitis case report https://pubmed.ncbi.nlm.nih.gov/24846587/
Caprylyl Glycol
No known risks
Humectant and preservative booster used to support product stability. Low systemic exposure expected from topical cosmetic use.
Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)
Coffea Arabica Seed Extract
No known risks
A fruit, seed or food-plant extract used for skin conditioning and antioxidant support. No pregnancy-specific signal was identified for the low topical exposure expected from a finished cosmetic. Direct pregnancy studies are generally unavailable, and botanical allergy remains possible.
Sources: European Commission CosIng ingredient inventory; CIR botanical safety framework and relevant fruit-derived ingredient assessments; peer-reviewed cosmetic and phytochemical literature for the named plants.
Sodium Hyaluronate
No known risks
Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Phenylpropanol
No known risks
A solvent or preservative-support ingredient used to dissolve actives and stabilise a formula. No reproductive or pregnancy-specific signal was identified for the low concentrations used in finished topical cosmetics. Solvents can still increase local irritation or the delivery of other formula ingredients.
Sources: European Commission CosIng ingredient inventory; European Chemicals Agency substance information; published dermal and cosmetic-use data for dimethyl isosorbide, phenylpropanol and benzyl glycol.
Citric Acid
No known risks
pH adjuster used in small amounts to maintain product stability. Not associated with pregnancy-specific concerns.
Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework
Potassium Chloride
No known risks
A common inorganic electrolyte used to control viscosity, stabilise a formula or condition skin. At cosmetic concentrations these salts do not present a pregnancy-specific concern; concentrated formulas can still sting damaged or very sensitive skin.
Sources: European Commission CosIng ingredient inventory; PubChem compound records for potassium chloride, magnesium chloride and calcium chloride; established pharmaceutical and food use of these electrolytes.
Glycerin
No known risks
Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Chlorphenesin
No known risks
Preservative used to help protect formulas from microbial growth. Reviewed cosmetic safety sources support present cosmetic use; no pregnancy- or breastfeeding-specific topical concern was identified in the material reviewed, although some users may still notice local irritation or sensitivity.
Sources: CIR: Safety Assessment of Chlorphenesin as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Tocopherol
No known risks
Vitamin E antioxidant used to protect oils and support the skin barrier. Not associated with pregnancy-specific concerns at cosmetic exposure.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Potassium Sorbate
No known risks
Preservative widely used in foods and cosmetics. Considered safe at regulated concentrations with low systemic exposure from topical use.
Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework
Sodium Benzoate
No known risks
Preservative widely used in foods and cosmetics. Considered safe at regulated concentrations with low systemic exposure from topical use.
Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework
Full recorded ingredient list
Water, Propanediol, Potassium Azeloyl Diglycinate, Polyacrylate Crosspolymer-6, Niacinamide, 3-O-Ethyl Ascorbic Acid, Caprylyl Glycol, Coffea Arabica Seed Extract, Sodium Hyaluronate, Phenylpropanol, Phenoxyethanol, Citric Acid, Potassium Chloride, Glycerin, Chlorphenesin, Tocopherol, Potassium Sorbate, Sodium Benzoate
Ingredient ratings refreshed 1 October 2026. Formulas vary by market and can change. Always compare with your packaging.
Questions about this assessment
Why does Naturium Azelaic Topical Acid 10% have a Low risk rating?
The recorded formula includes 1 ingredient entry with a risk flag: Phenoxyethanol (Low risk). These are ingredient-level flags; they do not replace the stored product assessment or account for every formulation detail. The product score is a stored assessment, not a clinical safety guarantee.
Does the niacinamide rating cover every ingredient in this product?
No. Niacinamide appears in the recorded formula, but its individual rating applies to that ingredient, not automatically to the whole product. Check the other ingredient ratings, any grey Not assessed entries and the stored product assessment. A niacinamide percentage or a product name is not a substitute for checking the full list.
Has every ingredient in Naturium Azelaic Topical Acid 10% been assessed?
18 of 18 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.
Does this assessment apply to my Naturium Azelaic Topical Acid 10%?
Only if the ingredient list on your packaging matches the recorded formula shown here. Formulas can differ by market and change over time. Compare the full list, not just the product name; report a mismatch if it differs.
Does this pregnancy assessment also establish breastfeeding suitability?
No. This page presents a pregnancy-focused product assessment. Do not infer a breastfeeding conclusion from its score or label; breastfeeding requires a separate assessment of the formula and how it is used.
