Naturium Niacinamide Serum 12% Plus Zinc 2% by Naturium
Naturium

Niacinamide Serum 12% Plus Zinc 2%

Serums

75/100
Low risk

Pregnancy-focused rating

Some ingredients carry a low-risk flag. Read the formulation context before deciding.

16 of 16 ingredients rated

Is it suitable during pregnancy?

MamaSkin rates the recorded formula for Naturium Niacinamide Serum 12% Plus Zinc 2% as Low risk (75/100). Review the ingredient context and any manual-review explanation before deciding.

Why this rating?

The recorded formula includes 2 ingredient entries with risk flags: Dimethicone (Low risk), Phenoxyethanol (Low risk). These are ingredient-level flags; they do not replace the stored product assessment or account for every formulation detail.

16 of 16 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.

How we assess products

Ingredient breakdown

The recorded formula, with evidence behind each rating. Unmatched ingredients are marked Not assessed in grey.

Ingredient ratings and evidence

Higher-risk flags first. Open an ingredient for evidence.

Phenoxyethanol

Low risk

Phenoxyethanol is a preservative permitted in EU cosmetics up to 1.0%. The SCCS concluded it is safe for cosmetic use at that level, including when considering higher cosmetic exposure scenarios in infants and young children. Main practical concern is irritation/stinging on very sensitive or compromised skin rather than a pregnancy- or breastfeeding-specific risk.

Sources: SCCS/1575/16: Phenoxyethanol opinion https://health.ec.europa.eu/publications/phenoxyethanol_en

Dimethicone

Low risk

Dimethicone is a silicone polymer used as a skin protectant and slip/conditioning agent. It is considered inert with minimal dermal absorption; the main practical issues are cosmetic (feel) and occasional irritation in very sensitive users. It is not a pregnancy-specific concern in topical cosmetic use.

Sources: CIR: Amended Safety Assessment of Dimethicone, Methicone, and Substituted-Methicone Polymers as Used in Cosmetics https://cir-safety.org/supplementaldoc/amended-safety-assessment-dimethicone-methicone-and-substituted-methicone-polymers-2

Water

No known risks

Water (Aqua) is the standard purified water used as a cosmetic solvent. It has no pregnancy-specific risk in normal topical use.

Sources: https://pubchem.ncbi.nlm.nih.gov/compound/Water, https://single-market-economy.ec.europa.eu/sectors/cosmetics/cosmetic-ingredient-database/cosing-glossary-ingredients_en

Niacinamide

No known risks

Niacinamide (vitamin B3) is widely used for barrier support and tone/texture benefits, and is generally considered safe in pregnancy and breastfeeding when used topically at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Propanediol

No known risks

Solvent and humectant used to improve texture and ingredient solubility. Low systemic exposure expected from topical cosmetic use.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Show all 16 ingredients

Glycerin

No known risks

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

Zinc PCA

No known risks

A zinc salt of pyrrolidone carboxylic acid used for skin conditioning, oil-control and antimicrobial support. Cosmetic safety reviewers concluded that the assessed zinc salts are safe in current cosmetic practices of use and concentration when formulated to be non-irritating. Zinc is an essential nutrient, but this entry assesses the low topical exposure from a finished cosmetic rather than supplements or medicinal doses. No pregnancy-specific topical concern was identified.

Sources: CIR: Safety Assessment of Zinc Salts as Used in Cosmetics https://www.cir-safety.org/supplementaldoc/safety-assessment-zinc-salts-used-cosmetics-1; CIR 146th Expert Panel Meeting final report record https://www.cir-safety.org/meeting/146th-cir-expert-panel-meeting

Polyacrylate Crosspolymer-11

No known risks

polyacrylate crosspolymer-11 is a cosmetic polymer, film former or high-molecular-weight texture aid. Systemic dermal absorption is expected to be limited when manufactured with appropriate residual-monomer and impurity controls. No pregnancy-specific concern was identified for normal cosmetic use; avoid inhaling airborne powder or spray droplets.

Sources: CIR polymer safety assessments and Quick Reference Table https://www.cir-safety.org/supplementaldoc/quick-reference-table-december-2025; European Commission CosIng ingredient inventory

Sodium Hyaluronate

No known risks

Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Caprylyl Glycol

No known risks

Humectant and preservative booster used to support product stability. Low systemic exposure expected from topical cosmetic use.

Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)

Xanthan Gum

No known risks

Natural polysaccharide thickener used for stability and texture. Not associated with pregnancy-specific concerns.

Sources: European cosmetics regulatory framework

Potassium Sorbate

No known risks

Preservative widely used in foods and cosmetics. Considered safe at regulated concentrations with low systemic exposure from topical use.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

Glyceryl Polyacrylate

No known risks

A high-molecular-weight polymer used for hydration and formula texture. Cosmetic safety reviewers concluded that glyceryl polyacrylate is safe in current practices. Absorption of the intact polymer is expected to be limited, and residual monomers should be controlled.

Sources: CIR: Glyceryl Polyacrylate final assessment, June 2022; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

Tocopheryl Acetate

No known risks

Tocopheryl acetate (vitamin E derivative) is used as an antioxidant and skin-conditioning ingredient; it is considered low concern in topical use with no known pregnancy or breastfeeding risks at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Hexylene Glycol

No known risks

Solvent and humectant used to improve texture and ingredient solubility in topical cosmetics. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR cosmetic ingredient safety references for alkane diols/glycols; EU CosIng / cosmetics regulatory inventory

Citric Acid

No known risks

pH adjuster used in small amounts to maintain product stability. Not associated with pregnancy-specific concerns.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

Full recorded ingredient list

Water, Niacinamide, Propanediol, Glycerin, Zinc PCA, Polyacrylate Crosspolymer-11, Sodium Hyaluronate, Dimethicone, Caprylyl Glycol, Phenoxyethanol, Xanthan Gum, Potassium Sorbate, Glyceryl Polyacrylate, Tocopheryl Acetate, Hexylene Glycol, Citric Acid

Ingredient ratings refreshed 1 October 2026. Formulas vary by market and can change. Always compare with your packaging.

Questions about this assessment

Why does Naturium Niacinamide Serum 12% Plus Zinc 2% have a Low risk rating?

The recorded formula includes 2 ingredient entries with risk flags: Dimethicone (Low risk), Phenoxyethanol (Low risk). These are ingredient-level flags; they do not replace the stored product assessment or account for every formulation detail. The product score is a stored assessment, not a clinical safety guarantee.

Does the niacinamide rating cover every ingredient in this product?

No. Niacinamide appears in the recorded formula, but its individual rating applies to that ingredient, not automatically to the whole product. Check the other ingredient ratings, any grey Not assessed entries and the stored product assessment. A niacinamide percentage or a product name is not a substitute for checking the full list.

Has every ingredient in Naturium Niacinamide Serum 12% Plus Zinc 2% been assessed?

16 of 16 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.

Does this assessment apply to my Naturium Niacinamide Serum 12% Plus Zinc 2%?

Only if the ingredient list on your packaging matches the recorded formula shown here. Formulas can differ by market and change over time. Compare the full list, not just the product name; report a mismatch if it differs.

Does this pregnancy assessment also establish breastfeeding suitability?

No. This page presents a pregnancy-focused product assessment. Do not infer a breastfeeding conclusion from its score or label; breastfeeding requires a separate assessment of the formula and how it is used.