Vitamin C Complex Serum

Vitamin C antioxidant used to support brightness and photoprotection; functions as an antioxidant/pH adjuster in cosmetic formulas. No pregnancy-specific contraindications are identified for topical cosmetic use.

Sources: CIR (Ascorbic Acid); PubMed (NLM)

An antioxidant peptide naturally present in the body and used in topical products for skin conditioning and tone. Clinical studies and systematic reviews report generally good tolerance of topical glutathione, although evidence for cosmetic benefits remains limited. No pregnancy-specific topical signal was identified.

Sources: PubMed: Systematic Review of the Efficacy and Safety of Topical Glutathione in Dermatology https://pubmed.ncbi.nlm.nih.gov/41416233/; PubMed: topical oxidized glutathione clinical trial https://pubmed.ncbi.nlm.nih.gov/25378941/

A fruit, seed or food-plant extract used for skin conditioning and antioxidant support. No pregnancy-specific signal was identified for the low topical exposure expected from a finished cosmetic. Direct pregnancy studies are generally unavailable, and botanical allergy remains possible.

Sources: European Commission CosIng ingredient inventory; CIR botanical safety framework and relevant fruit-derived ingredient assessments; peer-reviewed cosmetic and phytochemical literature for the named plants.

A papaya fruit extract used for skin conditioning. Cosmetic safety reviewers concluded that Carica papaya fruit and fruit-derived ingredients are safe in current cosmetic practices; this conclusion does not extend to papaya leaf extract, for which the available evidence was insufficient. No pregnancy-specific concern was identified for normal topical cosmetic exposure.

Sources: CIR: Safety Assessment of Carica papaya-Derived Ingredients as Used in Cosmetics, final 2025 https://cir-reports.cir-safety.org/view-attachment/?id=3ca24ad2-9f93-1b6c-a453-2da467b3c7c2

A botanical extract, juice or water used primarily for skin conditioning, moisturising, soothing or antioxidant support. Direct pregnancy studies of the named cosmetic material were not identified. No reproductive or developmental hazard was identified for normal topical exposure to a compliant finished cosmetic; oral herbal or medicinal use is outside this classification.

Sources: European Commission CosIng ingredient inventory; Cosmetic Ingredient Review botanical safety-assessment framework and relevant plant-family assessments. No ingredient-specific human pregnancy study of normal topical cosmetic use was identified.

A fruit, seed or food-plant extract used for skin conditioning and antioxidant support. No pregnancy-specific signal was identified for the low topical exposure expected from a finished cosmetic. Direct pregnancy studies are generally unavailable, and botanical allergy remains possible.

Sources: European Commission CosIng ingredient inventory; CIR botanical safety framework and relevant fruit-derived ingredient assessments; peer-reviewed cosmetic and phytochemical literature for the named plants.

Burdekin-plum fruit extract is supplied in a diluted glycerin/water matrix. This does not cover other plant parts, oral concentrates or engineered delivery. Ordinary diluted use on intact external skin is expected to produce low systemic exposure, with no identified pregnancy-specific concern for that preparation. This exposure-based conclusion does not mean pregnancy safety has been proven.

Sources: https://www.ellementalpro.com/download/1808_TDSs.pdf, https://www.ellementalpro.com/download/1808_SDSs.pdf

Illawarra-plum fruit extract is supplied in a diluted glycerin/water cosmetic matrix. Findings about other Podocarpus species or plant parts cannot automatically be assigned to this fruit preparation. Ordinary diluted use on intact external skin is expected to produce low systemic exposure, with no identified pregnancy-specific concern for that preparation. This exposure-based conclusion does not mean pregnancy safety has been proven.

Sources: https://www.ellementalpro.com/download/1808_TDSs.pdf, https://www.ellementalpro.com/download/1808_SDSs.pdf

Aloe barbadensis leaf juice is commonly used for soothing and hydration; topical use is considered low concern with no known pregnancy or breastfeeding risks, although rare sensitivities can occur.

Sources: CIR; EU/UK Cosmetics Regulation

Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Polymer thickener used to create gel textures. Large-molecule ingredient with negligible systemic absorption.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Tocopheryl acetate (vitamin E derivative) is used as an antioxidant and skin-conditioning ingredient; it is considered low concern in topical use with no known pregnancy or breastfeeding risks at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Humectant and preservative booster used to support product stability. Low systemic exposure expected from topical cosmetic use.

Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)

pH adjuster used in small amounts to maintain product stability. Not associated with pregnancy-specific concerns.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

Cellulose-derived thickener used to build viscosity and improve texture. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR Quick Reference Table / ingredient status (Hydroxyethylcellulose, Final Report 03/2009); EU CosIng / cosmetics regulatory inventory

pH adjuster used in very small quantities to balance formulations. Not associated with pregnancy-specific concerns.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

Film-forming polysaccharide used for soothing and hydration support. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Microbial Polysaccharide Gums as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Preservative widely used in foods and cosmetics. Considered safe at regulated concentrations with low systemic exposure from topical use.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

Solvent and humectant used to improve texture and ingredient solubility in topical cosmetics. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR cosmetic ingredient safety references for alkane diols/glycols; EU CosIng / cosmetics regulatory inventory

Sugar alcohol humectant used to help maintain water content at the skin surface. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Mannitol, Sorbitol, and Xylitol as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Natural polysaccharide thickener used for stability and texture. Not associated with pregnancy-specific concerns.

Sources: European cosmetics regulatory framework

A seaweed-derived polysaccharide used as a thickener and stabiliser. Cosmetic safety reviewers included algin in the plant polysaccharide gums group and concluded that the group is safe in current practices of use and concentration. No pregnancy-specific concern was identified for normal topical cosmetic use.

Sources: CIR: Safety Assessment of Plant Polysaccharide Gums as Used in Cosmetics https://www.cir-safety.org/sites/default/files/plpogu092014slr.pdf

Preservative acid used to help control microbial growth and support formula stability. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed; some users may still notice local irritation or stinging, especially on compromised skin.

Sources: CIR: Safety Assessment of Benzoic Acid and Sodium Benzoate as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Preservative acid used to help protect products from yeast, mould, and some bacteria. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed; some users may still notice local irritation or stinging, especially on reactive skin.

Sources: CIR: Safety Assessment of Sorbic Acid and Potassium Sorbate as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.

Sources: CIR; EU/UK Cosmetics Regulation

Preservative widely used in foods and cosmetics. Considered safe at regulated concentrations with low systemic exposure from topical use.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

An inorganic phosphate salt used mainly to buffer or adjust the pH of a formula. Cosmetic safety reviewers concluded that phosphoric acid and its simple salts, including disodium phosphate, are safe in current cosmetic use when products are formulated to avoid irritation. No pregnancy-specific concern is identified for normal topical exposure.

Sources: CIR: Safety Assessment of Phosphoric Acid and Its Simple Salts https://cir-safety.org/supplementaldoc/safety-assessment-phosphoric-acid-and-simple-salts-used-cosmetics-0

An insoluble mineral or elemental particle used for optical effects, absorbency or cosmetic texture. Meaningful systemic exposure through intact skin is expected to be low. No pregnancy- or reproductive-toxicity signal was identified for normal topical cosmetic use. Particle size, source purity, metal impurities and inhalation of airborne powder remain formulation-specific considerations, and local contact allergy is possible with gold.

Sources: European Commission CosIng ingredient inventory; SCCS guidance on the safety assessment of nanomaterials in cosmetics https://health.ec.europa.eu/scientific-committees/scientific-committee-consumer-safety-sccs_en; published cosmetic and dermatology literature for gold, diamond powder and perlite.

Nonionic emulsifier and solubilizer used to help oil and water phases mix. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified.

Sources: CIR: Safety Assessment of Polysorbates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

An inorganic phosphate salt used mainly to buffer or adjust the pH of a formula. Cosmetic safety reviewers concluded that phosphoric acid and its simple salts, including sodium phosphate, are safe in current cosmetic use when products are formulated to avoid irritation. No pregnancy-specific concern is identified for normal topical exposure.

Sources: CIR: Safety Assessment of Phosphoric Acid and Its Simple Salts https://cir-safety.org/supplementaldoc/safety-assessment-phosphoric-acid-and-simple-salts-used-cosmetics-0